Ozempic, a widely used medication for managing type 2 diabetes and weight loss, has recently garnered attention due to concerns over a potential side effect: hair loss. A new study explores whether semaglutide, the active ingredient in Ozempic, could contribute to thinning hair in some patients, especially among women.
Semaglutide, part of the GLP-1 class of drugs, has become a popular treatment not only for diabetes but also for weight management, with one in five people in the U.S. prescribed the drug. Dr. Raj Dasgupta, a quadruple board-certified physician at the University of Southern California, notes that GLP-1 drugs are known to help regulate blood sugar, reduce appetite, and slow digestion, providing significant benefits for those with obesity and diabetes.
However, the medication is not without its side effects. While gastrointestinal issues are well-documented, a recent study suggests that semaglutide may also be linked to hair loss in some users.
What the Study Found About Hair Loss and GLP-1 Drugs
The study, which looked at over 3,200 patients, found that about 60% of participants were using semaglutide (Ozempic), while the remaining 40% were on bupropion-naltrexone, a drug designed to curb appetite and control cravings. Researchers discovered that hair loss appeared to be more common among those using semaglutide, particularly women.
“The risk increase was under 1% for men and just over 2% for women,” said McCall McPherson, PA-C, founder of Modern Thyroid Clinic. “That means around two out of every 100 women on semaglutide may experience hair loss possibly tied to the drug.” Although the risk seems relatively small, McPherson emphasized the significance given the widespread use of these medications.
While McPherson has observed cases of hair loss in patients who used higher doses or experienced rapid appetite suppression, she stresses that with proper dosing, the issue is largely avoidable. In her clinic, which supports women with thyroid dysfunction-related weight loss issues, reducing the dosage often mitigates the side effects.
Dr. Steven Dayan, a plastic surgeon, has also noted increased reports of hair loss in postmenopausal women undergoing treatment with GLP-1 drugs. However, he cautions that the link between weight loss and hair thinning involves more than just the medication. “Massive weight loss, like stress, can also trigger hair loss,” he explained, adding that nutritional deficiencies may play a role, and studies need to account for these factors to determine the true cause.
Is Ozempic the Direct Cause of Hair Loss?
The study has raised questions about whether Ozempic is directly responsible for hair loss, with some experts casting doubt on its findings. Dr. Brynna Connor, a family medicine physician, pointed out that the semaglutide group in the study was older on average, which could mean other hormonal changes or deficiencies were contributing to hair loss, not just the medication itself.
Dr. Paul Rosenberg, a plastic surgeon, also expressed skepticism, noting the study’s limitations. He criticized the lack of randomization and crossover components in the research and emphasized the absence of biological measurements, such as bloodwork or hair samples, to more accurately assess the cause of hair loss. According to Dr. Rosenberg, a more thorough study would include a reversal period to observe whether hair loss recedes once the medication is stopped.
Despite these concerns, physicians are seeing real-world cases of hair thinning among Ozempic users. “I’ve definitely had patients mention hair thinning, especially if they’ve lost a lot of weight quickly,” Dr. Dasgupta acknowledged. “While it’s not the most common side effect, it’s something patients are noticing and discussing.”
How to Reduce the Risk of Hair Loss While Using Ozempic
Dr. Christina Han, a dermatologist, acknowledges that hair loss can be linked to rapid weight loss, which may stress the hair cycle. Although the study did not specify the type of hair loss, she offers several tips for minimizing the risk:
Lose Weight Gradually: “Slower, steadier weight loss is less stressful on the body,” Dr. Han advises. “Work with your doctor to set a healthy timeline for weight loss.”
Maintain Proper Nutrition: “Nutritional deficiencies, particularly in protein, iron, vitamin B, and vitamin D, can exacerbate hair loss,” she warns. “Ensure your diet remains balanced even while on medication.”
Focus on Mental Health: Stress management, adequate sleep, and overall wellness are crucial for maintaining healthy hair, Dr. Han adds.
Consult Your Doctor: If you notice hair thinning, it’s important to speak with your physician or a dermatologist early. “Medication-related hair shedding is typically temporary,” Dr. Han notes, but early intervention can help.
The Bottom Line
Dr. Dasgupta emphasizes that while GLP-1 drugs like Ozempic are highly effective for weight loss and managing diabetes, they do come with potential side effects, including hair loss, particularly in women. However, this side effect is generally temporary and manageable with proper care.
“Be patient with your body, focus on nutrition, and don’t hesitate to talk to your doctor if you have concerns about hair loss,” Dr. Dasgupta advises.
Related topics:
- Hair Loss After Weight Loss: Understanding the Connection
- Top 11 Hair Growth Vitamins for Longer, Thicker Hair
- Health Quiz: Which Nutrient Deficiency Can Lead to Hair Loss?
