For months, online discussions have suggested a potential link between Ozempic (semaglutide) and hair loss, but the connection has remained unclear. Now, a recent study has provided evidence supporting this claim, specifically noting that hair loss may be more pronounced in women. While the study’s findings are still in the early stages and have not yet been peer-reviewed, they have raised important questions about the possible side effects of this popular medication.
The Study: What It Found
Published on the pre-print server medRxiv, the study analyzed data from over 1,900 people taking semaglutide and compared them to 1,300 individuals using a different weight loss medication, bupropion-naltrexone (Contrave). Semaglutide, which is marketed under the brand names Ozempic and Wegovy, is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by slowing food movement in the gut and signaling the brain to reduce hunger, leading to weight loss.
The research focused on individuals using Wegovy, the FDA-approved version of semaglutide for obesity treatment, and found that those using semaglutide had a 50% higher chance of being diagnosed with a hair loss condition compared to those on Contrave. The risk of hair loss in women was found to be twice as high as in men. While the study urges more research to confirm these findings, it has sparked concerns about the medication’s potential impact on hair health.
Why Semaglutide Might Cause Hair Loss
It’s crucial to note that the study didn’t definitively prove that semaglutide causes hair loss, only that there is an association. However, doctors suggest that the medication may indeed contribute to hair loss, especially due to its effect on weight loss. Dr. Mir Ali, medical director at MemorialCare Surgical Weight Loss Center, explains that significant weight loss—whether through medication, diet, or surgery—is often linked to hair shedding. Rapid weight loss can disrupt the normal hair growth cycle, pushing hair from the growth phase to the shedding phase (telogen effluvium), leading to hair loss.
Moreover, people on semaglutide tend to consume fewer calories, which can lead to nutritional deficiencies, particularly in key nutrients like iron, zinc, and protein, all of which are crucial for healthy hair. Dr. Gary Goldenberg, assistant clinical professor of dermatology, adds that these deficiencies, compounded by common side effects like nausea, may weaken hair follicles and contribute to shedding. Additionally, semaglutide may affect hormones like cortisol, which could further impact hair health, particularly in women whose hair may be more sensitive to hormonal fluctuations.
How to Prevent and Treat Hair Loss from Semaglutide
While not everyone will experience hair loss on semaglutide, there are steps you can take to reduce the risk. Dr. Ali suggests ensuring an adequate intake of protein and taking any necessary vitamin supplements as recommended by your doctor. Dr. Goldenberg also advises monitoring your iron and zinc levels to prevent deficiencies.
Although biotin supplements are often touted for hair health, Dr. Ife J. Rodney, founder of Eternal Dermatology + Aesthetics, notes that biotin deficiency is unlikely to be the issue here. Instead, she recommends focusing on a balanced diet with plenty of fruits and vegetables to avoid nutritional deficiencies.
If you do notice hair loss while taking semaglutide, Dr. Rodney suggests using topical treatments like minoxidil, which is effective for both male and female pattern baldness as well as temporary shedding. If the problem persists, it may be helpful to consult with a dermatologist who can offer regenerative treatments to improve hair growth and reverse the effects of hair loss.
It’s important to remember that any hair loss from semaglutide is typically temporary. As weight stabilizes, hair often returns to its previous condition, according to Dr. Ali.
Conclusion
While the new study linking Ozempic (semaglutide) to hair loss raises valid concerns, it’s not cause for immediate alarm. Those using semaglutide should remain aware of the potential risks and take proactive steps to maintain their hair health. A balanced diet, proper supplementation, and regular check-ins with a healthcare provider can help mitigate the risk of hair loss. For those experiencing significant hair shedding, there are treatments available that can help restore hair growth over time.
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